Executive Order 14273

Lowering Drug Prices by Once Again Putting Americans First

Signed 2025-04-15 in effect
HealthcarePrescription DrugsPricing
HealthEconomy & Finance

Directs measures to lower prescription drug prices. Precursor to EO 14297.

Section by Section

What each section does, and how they differ.

Sec. 1 Purpose

First Administration delivered aggressive drug price actions; Biden Administration reversed progress; Inflation Reduction Act produced lower savings than projected.

Sec. 2 Policy

Federal health programs optimized to provide lower prescription drug access to patients and taxpayers.

Sec. 3 Improving upon the Inflation Reduction Act

Secretary proposes improved guidance within 60 days; Assistant works on Part D premium stabilization; Secretary seeks congressional modification of small molecule treatment.

Sec. 4 Reducing the Prices of High-Cost Drugs for Seniors

Secretary develops and tests payment model within one year to improve Medicare value for high-cost drugs.

Sec. 5 Appropriately Accounting for Acquisition Costs of Drugs in Medicare

Secretary publishes plan within 180 days for hospital acquisition cost survey and proposes appropriate adjustments.

Sec. 6 Promoting Innovation, Value, and Enhanced Oversight in Medicaid Drug Payment

Officials provide recommendations within 180 days on ensuring accurate rebates, promoting innovation, and supporting state spending management.

Sec. 7 Access to Affordable Life-Saving Medications

Secretary conditions future health center grants on establishing practices making insulin and epinephrine available at discounted rates within 90 days.

Sec. 8 Reevaluating the Role of Middlemen

Officials provide recommendations within 90 days on promoting competitive, efficient pharmaceutical value chains.

Sec. 9 Accelerating Competition for High-Cost Prescription Drugs

FDA Commissioner issues report within 180 days on accelerating generics, biosimilars, and over-the-counter reclassification.

Sec. 10 Increasing Prescription Drug Importation to Lower Prices

FDA Commissioner streamlines importation program within 90 days for state approval without sacrificing safety.

Sec. 11 Reducing Costly Care for Seniors

Secretary evaluates whether Medicare payment encourages hospital department shifts and proposes regulations within 180 days.

Sec. 12 Improving Transparency into Pharmacy Benefit Manager Fee Disclosure

Secretary of Labor proposes PBM transparency regulations within 180 days.

Sec. 13 Combating Anti-Competitive Behavior by Prescription Drug Manufacturers

Secretary conducts joint listening sessions and issues report with anti-competitive recommendations within 180 days.

Sec. 14 General Provisions

Standard boilerplate: preserves existing agency authority, conditions the order on appropriations, and creates no enforceable private rights.